Mechanism for the Antidepressant Effect of Ketamine Revealed – Neuroscience News

Mechanism for the Antidepressant Effect of Ketamine Revealed – Neuroscience News

Summary: Those with treatment-resistant depression showed significant improvement in symptoms and became more receptive to positive experiences following a one-week ketamine treatment regimen. Source: Paris Brain Institute Researchers from Inserm, CNRS, Sorbonne University and clinicians from the AP-HP and at Paris Brain Institute identified one of the mechanisms explaining ketamine effect as an antidepressant. Ketamine, … Read more

Ketamine and depression: A mechanism of the antidepressant revealed

Ketamine and depression: A mechanism of the antidepressant revealed

Mediation Results. Boxplots showing the IQRs for belief-updating biases (normalized by estimation error magnitude) and Montgomery-Åsberg Depression Rating Scale scores 24 h before and 1 wk after ketamine treatment. The black lines inside the boxplots show the median values, and the jitter elements left of each boxplot show the individual patients. EE indicates estimation error. … Read more