Christina Applegate reveals the mistake she made after her double mastectomy for breast cancer: ‘It was bulls—t’

Christina Applegate reveals the mistake she made after her double mastectomy for breast cancer: ‘It was bulls—t’

Christina Applegate’s unflinching honesty about life with multiple sclerosis (MS) has a backstory — and it’s rooted in regret.  Before she faced the autoimmune disease, the Emmy-winning actress battled breast cancer, and one choice she made during that fight would haunt her for years.  “Frankly, I was disgusted by what came out of my mouth,” … Read more

Christina Applegate details ‘excruciating agony’ of MS, from burning skin to numbness to diapers

Christina Applegate details ‘excruciating agony’ of MS, from burning skin to numbness to diapers

Christina Applegate is candidly revealing the horrific reality of living with the multiple sclerosis (MS) in her new memoir. The Emmy Award-winning actress was diagnosed with the chronic autoimmune disease in June 2021 at the age of 49 and shared the life-altering news with fans two months later. “I wish I could say that I … Read more

Christina Applegate makes rare comments about late boyfriend’s fatal drug overdose: ‘I tried everything’ 

Christina Applegate makes rare comments about late boyfriend’s fatal drug overdose: ‘I tried everything’ 

Christina Applegate is reflecting on a painful tragedy. During Tuesday’s episode of her “MeSsy” podcast, the 53-year-old actress and her co-host, Jamie-Lynn Sigler, spoke to their guest, Robert Iler, about his addiction battle, which sparked Applegate’s rare comments about her late boyfriend Lee Grivas, who died of a drug overdose in 2008. “I kind of … Read more

Christina Applegate hospitalized for painful infection as she continues MS battle

Christina Applegate hospitalized for painful infection as she continues MS battle

Christina Applegate can’t catch a break. The “Dead to Me” actress, 53, revealed she has been hospitalized for a kidney infection, which has since spread to both of her kidneys, as she continues to battle multiple sclerosis (MS). Applegate recounted the painful ordeal from her hospital bed in Los Angeles, Calif., while recording the Tuesday … Read more

Christina Applegate gets choked up over daughter: ‘She misses who I was before MS’

Christina Applegate gets choked up over daughter: ‘She misses who I was before MS’

Christina Applegate is sharing a heartbreaking truth about life with multiple sclerosis. The “Dead to Me” actress, 53, revealed how her 14-year-old daughter Sadie, whom she shares with her husband Martyn LeNoble, is dealing with her health battle. “I don’t get up in the morning with that, I get up because of her [my daughter],” … Read more

Christina Applegate experienced first MS symptoms in ‘Dead To Me’ pilot: ‘I remember falling’

Christina Applegate experienced first MS symptoms in ‘Dead To Me’ pilot: ‘I remember falling’

Christina Applegate is getting candid on her Multiple Sclerosis diagnosis. Although the actress, 53, wasn’t officially diagnosed until 2021, she first noticed mysterious symptoms two years earlier while shooting the pilot for the Netflix series “Dead To Me.” Applegate spoke about her experience on the Tuesday episode of her podcast, “Messy,” which she co-hosts with actress Jamie-Lynn Sigler, … Read more

Christina Applegate details sharp pains amid MS battle: ‘I lay in bed screaming’

Christina Applegate details sharp pains amid MS battle: ‘I lay in bed screaming’

Christina Applegate has shared the grueling effects of her battle with Multiple Sclerosis. The “Dead To Me” actress, who was diagnosed with MS in early 2021, has been open about how the condition — which affects the brain and nerves — has affected her daily life and Hollywood career. Speaking on Tuesday’s episode of her “MeSsy” podcast,… … Read more

Christina Applegate reunites with ‘Married… with Children’ TV Dad Ed O’Neill: ‘He raised me’

Christina Applegate reunites with ‘Married… with Children’ TV Dad Ed O’Neill: ‘He raised me’

Christina Applegate owes it all to her former TV dad, Ed O’Neill. Applegate, 52, reunited with O’Neill, 78, on Tuesday’s episode of her “MeSsy” podcast and they gushed over their relationship that started on the beloved sitcom “Married…with Children.” “I don’t even know how to explain this person,” said Applegate as she introduced O’Neill as … Read more

Christina Applegate was concerned about Will Ferrell’s marriage during ‘Anchorman’

Christina Applegate was concerned about Will Ferrell’s marriage during ‘Anchorman’

Not Ron Burgundy! Christina Applegate was worried about the state of Will Ferrell’s marriage to Viveca Paulin when they were filming 2004’s “Anchorman.” The former co-stars looked back on the misunderstanding on Tuesday’s episode of Applegate’s “MeSsy” podcast. “Christina, do you remember how you thought I was having marriage problems?” Ferrell, 56, asked. Will Ferrell … Read more

Everything Christina Applegate has said about daughter Sadie — including her reaction to her POTS diagnosis

Everything Christina Applegate has said about daughter Sadie — including her reaction to her POTS diagnosis

It’s an unbreakable bond. Christina Applegate has a loving relationship with her 13-year-old daughter, Sadie Grace LeNoble, who she shares with her husband, Martyn LeNoble. The mother-daughter duo have grown closer as they each deal with serious health issues. Applegate was diagnosed with multiple sclerosis in 2021 and has stepped away from acting. Christina Applegate and … Read more

Christina Applegate announces daughter Sadie, 13, was diagnosed with POTS

Christina Applegate announces daughter Sadie, 13, was diagnosed with POTS

Christina Applegate has revealed that her 13-year-old daughter has been diagnosed with POTS. The “Dead to Me” star’s daughter, Sadie, opened up about her condition on Tuesday’s episode of Applegate’s “MeSsy” podcast, saying she has newfound common ground with her mom, who is living with multiple sclerosis. “I have something called POTS,” Sadie shared. “I have … Read more

Christina Applegate clarifies she’s not on ‘suicide watch’ over MS battle — but does have ‘dark thoughts’

Christina Applegate clarifies she’s not on ‘suicide watch’ over MS battle — but does have ‘dark thoughts’

Christina Applegate cleared up recent comments she made about her difficult battle with multiple sclerosis. Earlier this month, the 52-year-old actress released an episode of her “MeSsy” podcast that was recorded at the beginning of 2024 and said that she doesn’t “enjoy living” because of her MS diagnosis. “I don’t enjoy it. I don’t enjoy things … Read more

Christina Applegate says she doesn’t ‘enjoy living’ anymore after MS diagnosis: ‘I’m trapped in this darkness’

Christina Applegate says she doesn’t ‘enjoy living’ anymore after MS diagnosis: ‘I’m trapped in this darkness’

Christina Applegate is in a dark place after being diagnosed with multiple sclerosis. The “Dead to Me” actress, 52, said that she’s “in a depression right now” on the June 4 episode of her “MeSsy” podcast with “The Sopranos” alum Jamie-Lynn Sigler, who also has MS. “Like a real, f–k it all depression where it’s kind of … Read more

Christina Applegate struggled with anorexia on ‘Married with Children,’ ate 5 almonds a day: ‘I wanted my bones to be sticking out’

Christina Applegate struggled with anorexia on ‘Married with Children,’ ate 5 almonds a day: ‘I wanted my bones to be sticking out’

Christina Applegate has “never discussed” her anorexia eating disorder until now. The “Dead to Me” actress and Jamie-Lynn Sigler opened up about suffering from eating disorders on the latest episode of their “MeSsy” podcast. “It was f–king torture,” Applegate, 52, said. “I just deprived myself of food for years and years and years.” Applegate revealed … Read more

Christina Applegate declined ‘RHOBH’ offer: Producer said I’d be ‘boring’

Christina Applegate declined ‘RHOBH’ offer: Producer said I’d be ‘boring’

Sorry, Andy. Television veteran and Emmy winner Christina Applegate was once asked to star in “The Real Housewives of Beverly Hills” — but declined the role. “I was asked to be a Housewife for Beverly Hills,” Applegate, 52, told her “MeSsy” podcast co-host Jamie-Lynn Sigler on Tuesday. “They asked me to be one probably… 10 years … Read more

Christina Applegate hasn’t showered in ‘3 weeks’ due to MS ‘relapse’

Christina Applegate hasn’t showered in ‘3 weeks’ due to MS ‘relapse’

Christina Applegate says she’s “in relapse right now” amid her multiple sclerosis battle. The 52-year-old “Dead to Me” actress revealed on her “MeSsy” podcast that the pain of the disease has made it difficult to tolerate bathing herself, so she’s slacking on her personal hygiene. “I’m gonna be honest with you, I need to buy stock in … Read more

Christina Applegate has 30 lesions on her brain amid painful MS battle: ‘It sucks’

Christina Applegate has 30 lesions on her brain amid painful MS battle: ‘It sucks’

Christina Applegate continues to be brutally honest about her battle with multiple sclerosis. The 52-year-old “Dead to Me” star revealed on the “Armchair Expert” podcast with co-hosts Dax Shepard and Monica Padman that she is in constant pain thanks to the autoimmune disorder. “I have 30 lesions on my brain,” Applegate claimed in Monday’s episode. “My biggest one … Read more

Christina Applegate questioned about Ozempic after losing 30 pounds amid MS battle

Christina Applegate questioned about Ozempic after losing 30 pounds amid MS battle

Christina Applegate is opening up about her battle with multiple sclerosis. The actress, who has hinted at retiring amid her health struggles, was diagnosed in 2021. The “Married… With Children” alum, 52, and Jamie-Lynn Sigler, 42, who also has MS, sat down with People where they spoke about the highs and lows of the disease. … Read more

Christina Applegate spotted this MS symptom 7 years before her diagnosis

Christina Applegate spotted this MS symptom 7 years before her diagnosis

Christina Applegate is sharing more heartbreaking details about her battle with multiple sclerosis.  During a Wednesday appearance on “Good Morning America,” Christina Applegate, 52, and her friend “Sopranos” alum Jamie-Lynn Sigler, 42, sat down with Robin Roberts. “My symptoms had started in the early part of 2021, and it was, like, literally just tingling on … Read more

Christina Applegate ‘blacked out’ at Emmys 2024 appearance: ‘I live kind of in hell’ with MS

Christina Applegate ‘blacked out’ at Emmys 2024 appearance: ‘I live kind of in hell’ with MS

She was the apple of their eye. Christina Applegate got candid about her multiple sclerosis diagnosis and rare 2024 Emmys appearance during a teaser clip for an upcoming interview on “Good Morning America.” “I live kind of in hell. I’m not out a lot, so this is a little difficult, just for my system,” Applegate, … Read more