Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS | NEJM

Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS | NEJM

Abstract Background The intrathecally administered antisense oligonucleotide tofersen reduces synthesis of the superoxide dismutase 1 (SOD1) protein and is being studied in patients with amyotrophic lateral sclerosis (ALS) associated with mutations in SOD1 (SOD1 ALS). Methods Download a PDF of the Research Summary. In this phase 3 trial, we randomly assigned adults with SOD1 ALS … Read more

Lupus Patients Go Into Remission in ‘Spectacular’ Immunotherapy Trial

Lupus Patients Go Into Remission in ‘Spectacular’ Immunotherapy Trial

Five seriously ill lupus patients have seen their disease driven into remission after a single infusion of modified immune cells, in a small trial that borrows from cancer therapy to harness patients’ own cells to treat the autoimmune condition. Scientists are calling the results “spectacular” and “incredibly exciting”, saying the findings may herald a new … Read more

R. Kelly convicted of six counts in federal trial in Chicago; co-defendants acquitted

R. Kelly convicted of six counts in federal trial in Chicago; co-defendants acquitted

Disgraced singer R. Kelly on Wednesday was convicted of multiple child pornography charges accusing him of sexually abusing his 14-year-old goddaughter on video nearly 20 years ago, but jurors acquitted him of charges he conspired with two associates to cover up the tapes and to obstruct justice in his 2008 child pornography trial in Cook … Read more

Megan Thee Stallion & Tory Lanez Trial: Kelsey Nicole Subpoenaed

Megan Thee Stallion & Tory Lanez Trial: Kelsey Nicole Subpoenaed

As the highly publicized trial was delayed, Megan’s former friend was ordered to return in December. The Megan Thee Stallion and Tory Lanez saga is far from over. According to reports, the criminal trial against Tory has been delayed yet again. On Wednesday (September 14), the “Say It” rapper, real name, Daystar Peterson, appeared in court for … Read more

R. Kelly’s federal trial in Chicago results in split verdict; singer faces possibility of longer prison term after conviction on child pornography charges

R. Kelly’s federal trial in Chicago results in split verdict; singer faces possibility of longer prison term after conviction on child pornography charges

It took more than two decades for “Jane” to come forward about the sexual abuse she suffered at the hands of her godfather, R&B superstar R. Kelly. And in the end, a federal jury in Chicago believed her. They believed her testimony that she was the one on the graphic videos directed by the Grammy-winning … Read more

R. Kelly convicted on many counts, acquitted of trial fixing

R. Kelly convicted on many counts, acquitted of trial fixing

CHICAGO (AP) — A federal jury on Wednesday convicted R. Kelly of several child pornography and sex abuse charges in his hometown of Chicago, delivering another legal blow to a singer who used to be one of the biggest R&B stars in the world. Kelly, 55, was found guilty on three counts of child pornography … Read more

Jurors in R. Kelly trial dismissed for the day after one is replaced; defense argument to resume Tuesday

Jurors in R. Kelly trial dismissed for the day after one is replaced; defense argument to resume Tuesday

After four weeks of testimony from nearly three dozen witnesses, closing arguments in the Chicago federal trial of R. Kelly and two co-defendants began Monday with a scathingly methodical presentation from prosecutors and a fire-and-brimstone statement on behalf of Kelly’s former business manager. Prosecutors at the Dirksen U.S. Courthouse started by reminding jurors of their … Read more