tolerance

‘Exciting’ new non-opioid painkiller shows promising results — and doesn’t build up tolerance

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‘Exciting’ new non-opioid painkiller shows promising results — and doesn’t build up tolerance

A real ache-ievement! Duke University researchers have devised a promising, potent pain reliever — seemingly without the harmful side effects and addictive highs of opioids. While opioids interact with numerous cellular pathways, the experimental drug is more selective. SBI-810 targets a receptor in the brain and spinal cord, activating a single pain-relief signal while steering … Read more

I was called a ‘drama queen’ with low pain tolerance — until I went blind

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I was called a ‘drama queen’ with low pain tolerance — until I went blind

A young woman claims she felt like a “drama queen” when she doctors told her she just had a “low pain tolerance.” She went blind in 48 hours later. Hazal Baybasin began experiencing excruciating headaches in 2019. The pain was so intense that the 32-year-old UK woman could hardly eat or sleep, couldn’t keep up … Read more