College students, rejoice — your all-nighters may have more benefits than earning you an A. That all-too-familiar “wired but tired” feeling due to lack of sleep for just one night might actually have antidepressant results, according to a study conducted by a team from Northwestern University. While chronic sleep deprivation has been studied at length, scientists … Read more
Summary: Those with treatment-resistant depression showed significant improvement in symptoms and became more receptive to positive experiences following a one-week ketamine treatment regimen. Source: Paris Brain Institute Researchers from Inserm, CNRS, Sorbonne University and clinicians from the AP-HP and at Paris Brain Institute identified one of the mechanisms explaining ketamine effect as an antidepressant. Ketamine, … Read more
Mediation Results. Boxplots showing the IQRs for belief-updating biases (normalized by estimation error magnitude) and Montgomery-Åsberg Depression Rating Scale scores 24 h before and 1 wk after ketamine treatment. The black lines inside the boxplots show the median values, and the jitter elements left of each boxplot show the individual patients. EE indicates estimation error. … Read more
Previous studies have shown that psychedelic drugs such as LSD (acid) and psilocybin (magic mushrooms) may potentially treat depression but can cause disturbing hallucinations in some cases. Researchers recently developed two novel compounds that target the same subtype of serotonin receptors as LSD and psilocybin but do not produce hallucinations. Like psychedelic substances, these novel … Read more