A fast-acting nasal spray offers hope for hard-to-treat depression: study

A fast-acting nasal spray offers hope for hard-to-treat depression: study

Rates of depression are historically high. Roughly one in six American adults have depression, and 30% of them have tried multiple medications without getting the relief they need. While the first-line treatments are still therapy and traditional antidepressant medications, others are making a splash, offering a different approach to treating this disorder. People are treating … Read more

Patrick Stewart’s final touching video gushed about love: ‘I hope it has brought pleasure and curiosity’

Patrick Stewart’s final touching video gushed about love: ‘I hope it has brought pleasure and curiosity’

Sir Patrick Stewart gushed about love in a touching final video recorded before his death at 86 — sharing what he hoped listeners would glean from his readings of Shakespeare’s sonnets. The celebrated English actor and Royal Shakespeare Company veteran’s final creative endeavors was an audio series dedicated to the Bard’s timeless works. “I hope … Read more

This family’s heartbreaking struggle with dementia in midlife may upend our understanding of the disease — and hope for a cure

This family’s heartbreaking struggle with dementia in midlife may upend our understanding of the disease — and hope for a cure

Do the crossword every day. Exercise 150 minutes per week. Follow the Mediterranean diet.  While for most people these commandments of healthy living lower the risk of developing dementia with advancing age, in some individuals cognitive decline is unrelated to what they do, or fail to do. It is coded in their DNA, tied to … Read more

Young woman urged to leave ‘red flag’ romance after sharing ‘clingy’ boyfriend’s texts: ‘I hope she runs’

Young woman urged to leave ‘red flag’ romance after sharing ‘clingy’ boyfriend’s texts: ‘I hope she runs’

A young woman has shared that she feels “smothered” by her “clingy” boyfriend after he started tracking her whereabouts. The 21-year-old said she’s been in a relationship with her 22-year-old boyfriend for nearly two years, but they recently took a month apart to focus on themselves. Since they rekindled their relationship, she has been overwhelmed … Read more

Hayden Panettiere voiced hope in heartbreaking last interview: ‘I have a lot more life left to live’

Hayden Panettiere spoke optimistically about the future in a heartbreaking interview just months before her shocking death, saying she had “a lot more life to live.” The “Nashville” and “Heroes” star told podcaster Jay Shetty in May that she was excited to move forward with her life after years of “darkness” and personal struggles. Hayden … Read more

New treatment offers hope for endometrial cancer patients

New treatment offers hope for endometrial cancer patients

A new treatment for endometrial cancer demonstrated strong potential in a Phase 3 clinical trial. Drugmaker Merck announced Monday that the investigational drug sacituzumab tirumotecan (sac-TMT) met its “primary endpoints” of overall survival and progression-free survival in patients with advanced or recurrent endometrial cancer. The TroFuse-005 trial is the first global Phase 3 trial to “demonstrate statistically significant … Read more

Consumer confidence plummeted to record low this month, study reveals — though spending shows a glimmer of hope

Consumer confidence plummeted to record low this month, study reveals — though spending shows a glimmer of hope

Consumer confidence across the United States plunged to an all-time low this month, as Americans grapple with anxiety over the war in Iran, new data revealed.  The University of Michigan’s long-running Survey of Consumers tracks how Americans feel about the economy, their personal finances and spending — shaped by factors like inflation, the cost of … Read more

Hope of the American Dream is still alive — but optimism greatly differs by demographic: survey

Hope of the American Dream is still alive — but optimism greatly differs by demographic: survey

More than half of people still believe that the American Dream is possible for those who want it — but optimism about achieving it greatly differs by demographic. That’s according to a new survey of 2,000 Americans (1,000 census-representative Hispanics and 1,000 non-Hispanics), which found that 61% of Hispanic respondents believe the American Dream is … Read more

Linda Cohn claps back at Keith Olbermann in media kerfuffle: ‘Hope you get the help you need’

Linda Cohn claps back at Keith Olbermann in media kerfuffle: ‘Hope you get the help you need’

The beef between ESPN’s Linda Cohn and Keith Olbermann, her former “SportsCenter” counterpart, escalated Friday. Cohn went scorched earth on Olbermann in response to his comments calling her “self-obsessed politically motivated clown,” saying that he ultimately needs to seek help. “Amazing @KeithOlbermann that you describe me how the world actually describes you,” Cohn posted to … Read more

Dolly Parton rest stops hope to make life on the road, travel more enjoyable

Dolly Parton rest stops hope to make life on the road, travel more enjoyable

The queen of country music is bringing her Southern hospitality to Tennessee highways in an effort to make travel more enjoyable. Dolly Parton announced the roll-out of Dolly’s Tennessean Travel Stops. The rest-stop areas will feature new and reimagined entertainment elements. “I have spent the bulk of my life on the road, and more specifically on a … Read more

Elton John reveals why he isn’t ‘giving up hope’ after ‘devastating’ loss of sight in right eye

Elton John reveals why he isn’t ‘giving up hope’ after ‘devastating’ loss of sight in right eye

He’s still standin’ after all this time. Elton John has revealed why he isn’t “giving up hope” after completely losing sight in his right eye from a serious infection last year. “It’s been devastating,” John, 78, told Variety in a cover story published Tuesday. “Because I lost my right eye and my left eye’s not … Read more

Dick Van Dyke looks forward to his 100th birthday: ‘I hope I make it’

Dick Van Dyke looks forward to his 100th birthday: ‘I hope I make it’

Dick Van Dyke is closing in on his 100th birthday. The 99-year-old actor revealed how he’s feeling about his upcoming milestone birthday on Dec. 13 in a new interview with People. “I hope I make it,” Van Dyke told the outlet while sitting beside his wife, Arlene Silver, 54, at their Malibu home. Dick Van … Read more

Can ‘Stranger Things’ Season 5 reverse the Broadway show’s godawful ticket sales?: ‘Holding onto hope’

Can ‘Stranger Things’ Season 5 reverse the Broadway show’s godawful ticket sales?: ‘Holding onto hope’

“Stranger Things: The First Shadow” has been runnin’ up that road, runnin’ up that hill for months on Broadway. Surprised observers feel like they’re in the Upside Down.  Wasn’t the play based on the Netflix series and produced by the streaming giant and Sonia Friedman Productions supposed to be a massive hit? Not so much. … Read more

Hope for sufferers of devastating brain disease as new treatment has 75% success rate

Hope for sufferers of devastating brain disease as new treatment has 75% success rate

A novel gene therapy has been found to significantly slow the progression of Huntington’s disease, offering new hope to sufferers of the incurable disorder that destroys brain cells over time. Drugmaker uniQure reported the results of its small but “groundbreaking” Phase I/II study this week, finding that a high dose of its AMT-130 therapy slowed … Read more

What is leucovorin? Inside the drug giving new hope to autism patients

What is leucovorin? Inside the drug giving new hope to autism patients

Can a generic drug designed to make chemotherapy work better benefit people with autism? President Trump is touting an “amazing” drug — leucovorin — as “an answer to autism,” a broad range of conditions that affect how people learn, behave, communicate and interact with others. A form of vitamin B9, also known as folate, leucovorin has been … Read more

‘The Office’ star Rainn Wilson may quit acting to become a death doula: ‘There’s a lot of hope to give people’

‘The Office’ star Rainn Wilson may quit acting to become a death doula: ‘There’s a lot of hope to give people’

Dwight Schrute, the death doula. Rainn Wilson revealed that he might quit Hollywood to pursue a very different profession during an appearance on “Late Night With Seth Meyers” on Wednesday, Sept. 3. “Well, as my celebrity star is fading – and it’s fine – I may put acting behind me,” the “Office” star began. “And there’s this … Read more

Lady Gaga cancels Miami concert minutes before showtime: ‘I hope you can forgive me’

Lady Gaga cancels Miami concert minutes before showtime: ‘I hope you can forgive me’

Mayhem in Miami. Lady Gaga abruptly canceled her concert in Florida Wednesday night just minutes before she was set to take the stage at Miami’s Kaseya Center. “Hi everyone, I am really so so sorry but I need to postpone tonight’s show in Miami,” the singer, 39, wrote on her Instagram Stories. Lady Gaga performs … Read more

Roger Daltrey, 81, ‘nervous’ about health ahead of The Who’s ‘grueling’ farewell tour: ‘Hope I make it through’

Roger Daltrey, 81, ‘nervous’ about health ahead of The Who’s ‘grueling’ farewell tour: ‘Hope I make it through’

Roger Daltrey has seen better days. The Who frontman, 81, admitted that he is “nervous” about his health as the “Baba O’Riley” band prepares to kick off their “The Song Is Over” farewell tour later this month. “This is certainly the last time you will see us on tour,” Daltrey told The Times during an … Read more

Martha Stewart takes aim at Meghan Markle and her lifestyle brand: ‘I hope she knows what she’s talking about’

Martha Stewart takes aim at Meghan Markle and her lifestyle brand: ‘I hope she knows what she’s talking about’

The queen of shade is back, and she’s taking no prisoners. Martha Stewart has made a not-so-subtle dig at aspiring lifestyle guru Meghan Markle following the launch of her As Ever brand. The original lifestyle extraordinaire, 83, didn’t mince words when asked about the Duchess of Sussex’s foray into the world of hosting — saying … Read more

Exclusive | ‘Dawson’s Creek’ creator Kevin Williamson gives hope for possible revival

Exclusive | ‘Dawson’s Creek’ creator Kevin Williamson gives hope for possible revival

Dawson may cry again.  “Dawson’s Creek” aired on The WB from 1998 to 2003, created by Kevin Williamson – and in this age of endless spinoffs and reboots, it’s possible that it could come back.  “Not in television form. I think there’s other ways that [a ‘Dawson’s Creek’ revival] can come to fruition,” Williamson, 60, … Read more